Octet RH96

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Octet RH96

Octet RH96

From IgG titration to epitope binning, the Octet® RH96 system delivers label-free molecular interaction analysis through state-of-the-art high-throughput platforms that facilitate the rapid characterization and development of biotherapeutic molecules.

  • Categories: Protein Analysis | Octet Label-Free Detection System |

  • Reads 8, 16, 32, 48, or 96 wells simultaneously.
  • The Octet® RH96 instrument read head provides design flexibility, allowing users to analyze 8, 16, 32, 48, or 96 samples simultaneously and achieve customized throughput of up to 96 samples.
  • Full-plate off-rate ranking in minutes.
  • The Dip and Read assay format enables rapid clone off-rate analysis, even in crude samples, using ready-to-use biosensors.
  • 96-well plate quantification in as little as two minutes.
  • IgG titer determination for an entire 96-well plate can be completed in two minutes. In addition, the sample plate compartment is compatible with 384-well plates, enabling even higher sample throughput.
  • 32 × 32 epitope binning in less than eight hours.
  • With the Octet® RH96 system, epitope binning can be completed in record time, allowing analysis of a 32 × 32 antibody matrix in less than eight hours. Dedicated epitope binning analysis software enables easy visualization and interpretation of large datasets.
  • The microfluidics-free Dip and Read format reduces assay time and maintenance costs.
  • The Octet® RH96 system uses Dip and Read technology, in which biosensors are immersed directly into samples contained in microplates. Since no fluidics are involved, Octet® systems provide greater uptime and lower operating costs.

Applications

ELISA Conversion

ELISA assays are well known for result variability, susceptibility to human error, and long turnaround times. High-throughput Octet® systems are designed to overcome these limitations. Convert your ELISA assay into an Octet® assay.

Epitope Binning

Epitope binning identifies and classifies antibody candidates that bind to similar epitope regions on an antigen. Octet® epitope binning assays are based on testing the sequential binding capability of two antibodies against a single antigen. Fast assay times, high throughput, exceptional reproducibility, and dedicated software tools make Octet® platforms ideal for analyzing large antibody libraries.

Protein Contaminant Testing

Protein contaminants represent a significant challenge during biopharmaceutical manufacturing. The rapid, high-throughput protein analysis capabilities of the Octet® platform, combined with Anti-CHO HCP and Residual Protein A kits, provide biopharmaceutical developers with a fast and easy-to-use solution for contaminant testing.