Crossflow Systems
Sartorius offers flexible tangential flow filtration systems for process development in laboratory environments and clinical trials, as well as for commercial production batches. Whether you are looking for a cost-effective multi-use solution or a functionally closed solution with single-use flow paths for aseptic processing, our TFF portfolio provides the right option to meet your individual requirements.
Screening 5 mL – 500 mL | 10 mg – 5 g
With Ambr® Crossflow, Sartorius offers a high-throughput solution for parallel screening. It enables access to molecule behavior in the early stages of development.
Development 20 mL – 5 L | 0.5 g – 50 g
Sartoflow® Smart is an ideal crossflow system for process development. Achieve the highest product yield with its low-shear membrane pump.
Process Development / Preclinical 2 – 50 L | 20 g – 500 g
Sartoflow® Advanced offers flexible TFF solutions to meet your individual requirements. Find the right technology to accelerate your process development and support your small-scale production.
Pilot and Clinical 20 – 500 L | 200 g – 5 kg
Qualified and compliant pilot or clinical process-scale systems designed to enable fast and flexible cGMP scale-up of bioprocesses.
Commercial Production 100 – 2,000 L | 500 g – 20 kg
Robust commercial production-scale systems covering larger outputs for cGMP single-use biological purification.
- Categories: Process-Scale Filtration | Crossflow Filtration |
Choose from high-throughput Ambr® Crossflow for screening, configurable Sartoflow® benchtop devices for early- and late-stage process development, or scale up to customized or multifunctional cGMP-compliant modular system platforms for clinical and commercial production.
Accelerate time to market and expand production capacity requirements with maximum equipment utilization. Reduce the risk of operator error and significantly shorten your development time in both single-use and hybrid processes.
Crossflow Systems
Process Solutions for Ultrafiltration and Diafiltration
Sartorius offers flexible tangential flow filtration systems for process development in laboratory environments and clinical trials, as well as for commercial production batches. Whether you are looking for a cost-effective multi-use solution or a functionally closed solution with single-use flow paths for aseptic processing, our TFF portfolio provides the right option to meet your individual requirements.
SARTOFLOW® Study
Your best support in ultra- and diafiltration
This manual benchtop Crossflow system is optimized for ultrafiltration, microfiltration, and diafiltration applications used in many downstream processes.
SARTOFLOW® Smart
Excellent flexibility
Ideal for membrane surface areas from 50 cm² to 0.14 m².
Intuitive and user-friendly.
One operating design and predefined sequences for all SARTOFLOW® systems.
Highest product yield with a low-shear 4-piston membrane pump.
Ambr® Crossflow
4-channel system including control station
Operating factors for manufacturability.
Gather important information at an earlier stage about the behavior of molecules in downstream processes.
Automated, parallel trials.
Up to 16 channels can be managed by a single control station.
Lowest process volumes.
Small-scale screening with 10 cm² membrane area | 5 mL recirculation.